{"product_id":"igf-1-lr3-1mg-maximizacao-de-resultados-musculares-diluente-genpharma","title":"IGF-1 LR3 1mg - Maximização de Resultados Musculares +Diluente (Genpharma)","description":"\u003ch2 style=\"box-sizing: border-box; font-family: 'Segoe UI'; border-bottom: 1px solid #e5dcc3; color: #e26703; font-size: 15px; margin: 0px 0px 15px; padding: 0px 0px 1px;\"\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eImagem meramente ilustrativa.\u003c\/span\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eAs representações visuais não correspondem necessariamente ao produto final.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"box-sizing: border-box; font-family: 'Segoe UI'; border-bottom: 1px solid #e5dcc3; color: #e26703; font-size: 15px; margin: 0px 0px 15px; padding: 0px 0px 1px;\"\u003e\u003cbr\u003e\u003c\/h2\u003e\n\u003ch2 style=\"box-sizing: border-box; font-family: 'Segoe UI'; border-bottom: 1px solid #e5dcc3; color: #e26703; font-size: 15px; margin: 0px 0px 15px; padding: 0px 0px 1px;\"\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eCompre IGF-1 LR3 Premium 1mg:\u003c\/span\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3 id=\"Sample_IGF1_LR3_Dosage_Protocol\" class=\"uabb-toc-text\" style=\"box-sizing: border-box; border: 0px; font-size: 1.38889rem; outline: 0px; padding: 0px; vertical-align: baseline; clear: both; line-height: 1.3em; font-family: 'IBM Plex Sans', sans-serif; background-color: #ffffff; user-select: text !important; color: #333333 !important; text-align: left; margin: 1em !important 0px 0.7em !important 0px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eProtocolo de dosagem de IGF-1 LR3 \u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"box-sizing: border-box; border: 0px; font-size: 18px; outline: 0px; padding: 0px; vertical-align: baseline; font-family: Proxima-Nova, proxima-nova, sans-serif; background-color: #ffffff; user-select: text !important; margin-bottom: 1em !important; text-align: left;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003ePara fins de referência, segue um exemplo de protocolo de IGF-1 LR3 que pesquisadores podem administrar a indivíduos para observar a proliferação celular e a hipertrofia muscular:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul style=\"box-sizing: border-box; border: 0px; font-size: 18px; margin: 0px 0px 1.5em 3em; outline: 0px; padding: 0px; vertical-align: baseline; list-style-position: initial; list-style-image: initial; font-family: Proxima-Nova, proxima-nova, sans-serif; background-color: #ffffff; user-select: text !important; text-align: left;\"\u003e\n\u003cli style=\"box-sizing: border-box; border: 0px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; user-select: text !important;\"\u003e\n\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eDosagem diária:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003e\u003cspan\u003e \u003c\/span\u003e100mcg.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"box-sizing: border-box; border: 0px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; user-select: text !important;\"\u003e\n\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eFrequência:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003e Administrar injeção subcutânea uma vez ao dia durante todo o período do estudo.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"box-sizing: border-box; border: 0px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; user-select: text !important;\"\u003e\n\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eDuração do estudo:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003e\u003cspan\u003e \u003c\/span\u003e4-6 semanas\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"box-sizing: border-box; border: 0px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; user-select: text !important;\"\u003e\n\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eObservações:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003e\u003cspan\u003e \u003c\/span\u003eNão administre a dose menos de duas horas antes de dormir devido ao risco de supressão da síntese natural do hormônio do crescimento. Um estudo de seis semanas com 100 mcg\/dia exigirá quatro frascos de IGF-1 LR3 1 mg\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"no-more-tables\" style=\"box-sizing: border-box; color: #333333; font-family: 'Segoe UI'; font-size: 14px;\"\u003e\n\u003ctable border=\"1px\" width=\"663.484\" cellspacing=\"0\" cellpadding=\"0\" style=\"border-collapse: collapse; width: 100%; height: 252px; background-color: #ffffff; border-color: #843FA1; border-style: solid;\"\u003e\n\u003ctbody style=\"box-sizing: border-box;\"\u003e\n\u003ctr class=\"bg_color\" style=\"box-sizing: border-box; background: #b3d4fc; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eTamanho da unidade\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e1 mg\/\u003cspan style=\"color: #000000;\"\u003efrasco\u003c\/span\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"box-sizing: border-box; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eQuantidade unitária\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e1 frasco\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"bg_color\" style=\"box-sizing: border-box; background: #b3d4fc; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003ePureza (Espectrometria de Massa e UV)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e99,81%\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"box-sizing: border-box; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eSequência\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eMFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"bg_color\" style=\"box-sizing: border-box; background: #b3d4fc; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eFórmula Molecular\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\n\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eC \u003c\/span\u003e\u003csub style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e400\u003c\/span\u003e\u003c\/sub\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e H \u003c\/span\u003e\u003csub style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e625\u003c\/span\u003e\u003c\/sub\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e N \u003c\/span\u003e\u003csub style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e111\u003c\/span\u003e\u003c\/sub\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e O \u003c\/span\u003e\u003csub style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e115\u003c\/span\u003e\u003c\/sub\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e S \u003c\/span\u003e\u003csub style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e9\u003c\/span\u003e\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"box-sizing: border-box; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eAparência\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003ePó branco liofilizado\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"bg_color\" style=\"box-sizing: border-box; background: #b3d4fc; height: 18px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eFonte\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 18px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eSíntese recombinante\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"box-sizing: border-box; height: 72px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 72px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eArmazenar\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 72px;\"\u003e\n\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eO IGF-1 LR3 liofilizado é estável à\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003etemperatura ambiente por 90 dias; no entanto, é melhor armazená-lo em um refrigerador\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eabaixo de 8°C para qualquer\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eperíodo de tempo prolongado.\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr class=\"bg_color\" style=\"box-sizing: border-box; background: #b3d4fc; height: 54px;\"\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 54px;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eTermos\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"box-sizing: border-box; border: 1px solid #f5f5f5; font-size: 13px; padding: 5px; height: 54px;\"\u003e\n\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eOs produtos que oferecemos destinam-se\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003eexclusivamente ao uso em pesquisa laboratorial. Por favor, familiarize-se com\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003enossos termos\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; vertical-align: inherit;\"\u003e antes de fazer seu pedido.\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2 id=\"whatis\" style=\"box-sizing: border-box; line-height: 42px; font-size: 30px; margin: 0px 0px 30px; font-family: arimo, arial, sans-serif; position: sticky; top: 25px; color: #000000; min-width: 317px; max-width: 317px; padding-right: 30px; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eO que é IGF1-LR3?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003e\u003cspan style=\"color: #000000; font-family: arimo, arial, sans-serif; font-size: medium; background-color: #ffffff;\"\u003eIGF1-LR3 é uma versão modificada do fator de crescimento semelhante à insulina 1 (IGF-1). O nome completo do peptídeo é fator de crescimento semelhante à insulina 1 com arginina longa 3. Todos os derivados de IGF-1 desempenham papéis importantes na divisão celular, proliferação celular e comunicação intercelular. Embora tenha efeitos semelhantes, o IGF-1 LR3 não se liga às proteínas de ligação ao IGF com a mesma força que o IGF-1. Isso resulta em uma permanência do IGF1-LR3 na corrente sanguínea 120 vezes maior que a do IGF-1. O IGF1-LR3 adquire sua meia-vida prolongada como resultado de suas alterações estruturais. O peptídeo é criado pela adição de 13 aminoácidos à extremidade N-terminal do IGF-1 e pela conversão do ácido glutâmico na posição 3 do IGF-1 em um resíduo de arginina.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2 id=\"structure\" style=\"box-sizing: border-box; line-height: 42px; font-size: 30px; margin: 0px 0px 30px; font-family: arimo, arial, sans-serif; position: sticky; top: 25px; color: #000000; min-width: 317px; max-width: 317px; padding-right: 30px; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003eEstrutura IGF1-LR3\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eSequência:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e  MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box; user-select: text !important; word-break: break-word;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eFórmula Molecular:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e  C400H625N111O115S9\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box; user-select: text !important; word-break: break-word;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003ePeso Molecular:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e  9117,5 g\/mol\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box; user-select: text !important; word-break: break-word;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eNúmero CAS:\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e  946870-92-4\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003ca title=\"Estrutura molecular da kisspeptina-10\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: underline; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; user-select: text !important;\"\u003e\u003cimg src=\"https:\/\/www.peptidesciences.com\/media\/wysiwyg\/igf1-structure.png\" alt=\"Estrutura\" width=\"350\" height=\"350\" loading=\"lazy\" style=\"box-sizing: border-box; user-select: text !important; max-width: 100%; height: auto; border: 0px none; display: block; word-break: break-word;\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2 id=\"research\" style=\"box-sizing: border-box; line-height: 42px; font-size: 30px; margin: 0px 0px 30px; font-family: arimo, arial, sans-serif; position: sticky; top: 25px; color: #000000; min-width: 317px; max-width: 317px; padding-right: 30px; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003ePesquisa sobre IGF1-LR3\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3 style=\"box-sizing: border-box; line-height: 25.2px; font-size: 18px; margin: 0px 0px 20px; font-family: arimo, arial, sans-serif; word-break: break-word; color: #000000; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; word-break: break-word; font-size: medium; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eDivisão celular\u003c\/span\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eAssim como o IGF-1, o IGF1-LR3 é um potente estímulo para a divisão e proliferação celular. Seus principais efeitos se manifestam em tecidos conjuntivos como músculos e ossos, mas também promove a divisão celular no fígado, rins, nervos, pele, pulmões e tecidos sanguíneos. O IGF-1 é melhor compreendido como um hormônio da maturação, pois não apenas promove a proliferação celular, mas também a diferenciação. Em outras palavras, o IGF-1 induz a maturação celular, permitindo que as células desempenhem suas funções específicas.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eAo contrário do IGF-1, o IGF1-LR3 permanece na corrente sanguínea por longos períodos. Essa propriedade torna o IGF1-LR3 uma molécula muito mais potente. Uma dose de IGF1-LR3 proporciona aproximadamente três vezes mais ativação celular do que uma dose similar de IGF-1.  \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eObserve que o IGF1-LR3 e todos os derivados do IGF-1 não promovem o aumento do tamanho das células (hipertrofia), mas sim a divisão e proliferação celular (hiperplasia). No caso do músculo, por exemplo, o IGF1-LR3 não faz com que as células musculares aumentem de tamanho, mas aumenta o número total de células musculares.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"box-sizing: border-box; line-height: 25.2px; font-size: 18px; margin: 0px 0px 20px; font-family: arimo, arial, sans-serif; word-break: break-word; color: #000000; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; word-break: break-word; font-size: medium; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eMetabolismo de gordura e diabetes\u003c\/span\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eO IGF1-LR3 estimula o metabolismo de gordura de forma indireta, ligando-se tanto ao receptor IGF-1R quanto ao receptor de insulina. Essas ações aumentam a captação de glicose do sangue pelas células musculares, nervosas e hepáticas. Isso resulta em uma diminuição geral dos níveis de açúcar no sangue, o que, por sua vez, leva o tecido adiposo e o fígado a iniciarem a quebra de glicogênio e triglicerídeos. No geral, isso produz uma redução líquida do tecido adiposo e um consumo líquido de energia (ou seja, catabolismo líquido).\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eDado o seu papel na redução dos níveis de açúcar no sangue, não é de surpreender que o IGF1-LR3 reduza os níveis de insulina, bem como a necessidade de insulina exógena no diabetes. Na maioria dos casos, isso se traduz em uma diminuição de 10% na necessidade de insulina para manter os mesmos níveis de açúcar no sangue. Esse fato pode ajudar os cientistas a entender como diminuir as doses de insulina em indivíduos com baixa sensibilidade à insulina e pode até mesmo oferecer informações sobre como prevenir o diabetes tipo 2.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"box-sizing: border-box; line-height: 25.2px; font-size: 18px; margin: 0px 0px 20px; font-family: arimo, arial, sans-serif; word-break: break-word; color: #000000; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; word-break: break-word; font-size: medium; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003ePrejudica a miostatina\u003c\/span\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eA miostatina (também conhecida como fator de diferenciação de crescimento 8) é uma proteína muscular que inibe principalmente o crescimento e a diferenciação das células musculares. Embora essa função seja importante para prevenir a hipertrofia descontrolada e garantir a recuperação adequada após lesões, há momentos em que a inibição da miostatina pode ser benéfica. A capacidade de impedir a ação da miostatina pode ser útil em condições como a distrofia muscular de Duchenne (DMD) ou em pessoas que sofrem perda muscular durante períodos prolongados de imobilidade. Nesses casos, a inibição dessa enzima natural pode ajudar a retardar a degradação muscular, manter a força e prevenir complicações.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eEm modelos de DMD em ratos, descobriu-se que o IGF1-LR3 e outros derivados do IGF-1 são capazes de neutralizar os efeitos negativos da miostatina, protegendo as células musculares e prevenindo a apoptose. O IGF1-LR3, graças à sua longa meia-vida, é altamente eficaz na neutralização da miostatina e parece funcionar ativando uma proteína muscular chamada MyoD \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-size: 16px; line-height: 0; position: relative; vertical-align: baseline; top: 0px; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e[\u003c\/span\u003e\u003c\/span\u003e\u003ca title=\"“IGF-1 secretado por células-tronco derivadas do tecido adiposo protege mioblastos do efeito negativo da miostatina.” [Online]. Disponível em: https:\/\/www.hindawi.com\/journals\/bmri\/2014\/129048\/. [Acesso em: 16 de maio de 2019].\" href=\"https:\/\/www.peptidesciences.com\/igf-1-lr3-1mg#resources\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; position: relative; top: 7px; display: inline-block; vertical-align: top; font-size: 9.6px; line-height: 1; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e1\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e], [\u003c\/span\u003e\u003c\/span\u003e\u003ca title=\"N. Li, Q. Yang, RG Walker, TB Thompson, M. Du e BD Rodgers, “A atenuação da miostatina in vivo reduz a adiposidade, mas ativa a adipogênese”, Endocrinologia, vol. 157, nº 1, pp. 282–291, janeiro de 2016.\" href=\"https:\/\/www.peptidesciences.com\/igf-1-lr3-1mg#resources\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; position: relative; top: 7px; display: inline-block; vertical-align: top; font-size: 9.6px; line-height: 1; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e2\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eMyoD\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e é a proteína normalmente ativada pelo exercício (por exemplo, levantamento de peso) ou lesão tecidual e é responsável pela hipertrofia muscular.\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"box-sizing: border-box; line-height: 25.2px; font-size: 18px; margin: 0px 0px 20px; font-family: arimo, arial, sans-serif; word-break: break-word; color: #000000; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; word-break: break-word; font-size: medium; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003ePesquisa sobre longevidade IGF1-LR3\u003c\/span\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eO IGF1-LR3 promove o reparo e a manutenção dos tecidos em todo o corpo, tornando-se uma molécula protetora contra danos celulares e os efeitos do envelhecimento. Pesquisas em bovinos e suínos indicam que a administração de IGF1-LR3 pode ser uma solução eficaz para atenuar os efeitos do envelhecimento celular. Pesquisas em andamento com camundongos buscam determinar se o IGF1-LR3 pode ser útil na prevenção da progressão de uma ampla gama de doenças, como demência, atrofia muscular e doença renal. Esta pesquisa revela que a administração de IGF-1 pode prolongar a vida e reduzir a incapacidade \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-size: 16px; line-height: 0; position: relative; vertical-align: baseline; top: 0px; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e.\u003c\/span\u003e\u003c\/span\u003e\u003ca title=\"E. Corpas, SM Harman e MR Blackman, “Hormônio do crescimento humano e envelhecimento humano”, Endocr. Rev., vol. 14, nº 1, pp. 20–39, fev. 1993.\" href=\"https:\/\/www.peptidesciences.com\/igf-1-lr3-1mg#resources\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; position: relative; top: 7px; display: inline-block; vertical-align: top; font-size: 9.6px; line-height: 1; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e3\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e], [\u003c\/span\u003e\u003c\/span\u003e\u003ca title=\"WE Sonntag, A. Csiszar, R. deCabo, L. Ferrucci e Z. Ungvari, “Diversos papéis do hormônio do crescimento e do fator de crescimento semelhante à insulina-1 no envelhecimento dos mamíferos: progresso e controvérsias”, J. Gerontol. A. Biol. Ciência. Med. Ciência, vol. 67, não. 6, pp. 587–598, junho de 2012.\" href=\"https:\/\/www.peptidesciences.com\/igf-1-lr3-1mg#resources\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; position: relative; top: 7px; display: inline-block; vertical-align: top; font-size: 9.6px; line-height: 1; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e4\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e], [\u003c\/span\u003e\u003c\/span\u003e\u003ca title=\"“Sistema IGF-I\/IGFBP: panorama do metabolismo e exercício físico. - PubMed - NCBI.” [Online]. Disponível em: https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22714057. [Acesso em: 16 de maio de 2019].\" href=\"https:\/\/www.peptidesciences.com\/igf-1-lr3-1mg#resources\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; position: relative; top: 7px; display: inline-block; vertical-align: top; font-size: 9.6px; line-height: 1; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e5\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e, p. 1]\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e .\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; vertical-align: inherit;\"\u003e\u003cimg src=\"https:\/\/www.peptidesciences.com\/media\/wysiwyg\/igf1-diagram.png\" alt=\"A expectativa de vida de camundongos machos e fêmeas está correlacionada com os níveis de IGF-1.\" width=\"627\" height=\"291\" loading=\"lazy\" style=\"box-sizing: border-box; max-width: 100%; height: auto; border: 0px none; display: block; word-break: break-word; color: #000000; font-family: arimo, arial, sans-serif; font-size: 16px; background-color: #ffffff; user-select: text !important;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: x-small;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eA expectativa de vida de camundongos machos e fêmeas está correlacionada com os níveis de IGF-1.\u003c\/span\u003e\u003c\/span\u003e\u003cbr style=\"box-sizing: border-box; user-select: text !important; word-break: break-word;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: x-small;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eFonte:  \u003c\/span\u003e\u003c\/span\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/224811043_Diverse_Roles_of_Growth_Hormone_and_Insulin-Like_Growth_Factor-1_in_Mammalian_Aging_Progress_and_Controversies\" rel=\"nofollow noopener\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; user-select: text !important;\" target=\"_blank\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eResearchGate\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"box-sizing: border-box; line-height: 25.2px; font-size: 18px; margin: 0px 0px 20px; font-family: arimo, arial, sans-serif; word-break: break-word; color: #000000; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; word-break: break-word; font-size: medium; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eSinalização de glicocorticoides\u003c\/span\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eOs glicocorticoides, secretados principalmente pelas glândulas suprarrenais, são medicamentos clínicos importantes usados para controlar a dor e reduzir a inflamação em doenças autoimunes, lesões neurológicas, câncer e outras condições. Infelizmente, os glicocorticoides apresentam diversos efeitos colaterais indesejáveis, como perda de massa muscular, ganho de gordura e deterioração da densidade óssea. Há interesse no uso do IGF1-LR3 para reduzir os efeitos colaterais dos glicocorticoides e, assim, permitir uma terapia mais eficaz \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-size: 16px; line-height: 0; position: relative; vertical-align: baseline; top: 0px; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e.\u003c\/span\u003e\u003c\/span\u003e\u003ca title=\"Por Hanaoka, CA Peterson, C. Horbinski e LJ Crofford, “Implicações da terapia com glicocorticoides em miopatias inflamatórias idiopáticas”, Nat. Rev. Rheumatol., vol. 8, nº 8, pp. 448–457, agosto de 2012.\" href=\"https:\/\/www.peptidesciences.com\/igf-1-lr3-1mg#resources\" style=\"box-sizing: border-box; color: #e7461e; text-decoration-line: none; background: 0px 0px; transition: color 0.3s; text-underline-offset: 0.14em; word-break: break-word; position: relative; top: 7px; display: inline-block; vertical-align: top; font-size: 9.6px; line-height: 1; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e6\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e]\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003e .\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; font-size: medium;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eO IGF1-LR3 apresenta efeitos colaterais mínimos a moderados, baixa biodisponibilidade oral e excelente biodisponibilidade subcutânea em camundongos. A dosagem por kg em camundongos não é escalável para humanos. O IGF1-LR3 à venda na Peptide Sciences destina-se exclusivamente a fins educacionais e de pesquisa científica, não sendo apropriado para consumo humano. Compre IGF1-LR3 somente se você for um pesquisador licenciado.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003col style=\"box-sizing: border-box; margin: 0px; padding: 0px; word-break: break-word; position: relative; counter-reset: num 0; list-style: none; color: #000000; font-family: arimo, arial, sans-serif; font-size: 16px; background-color: #ffffff; user-select: text !important;\"\u003e\n\u003cli style=\"box-sizing: border-box; margin: 0px 0px 40px; padding: 0px 0px 0px 46px; word-break: break-word; position: relative; counter-increment: num 1; width: 635px; line-height: 25.6px; color: #6b6b6b; transition: color 0.2s; user-select: text !important; text-align: left;\"\u003e\u003cbr\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan style=\"box-sizing: border-box; user-select: text !important; font-weight: bold; word-break: break-word;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eTodos os artigos e informações sobre produtos fornecidos neste site têm caráter meramente informativo e educacional.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"box-sizing: border-box; margin-bottom: 30px; word-break: break-word; line-height: 25.6px; font-size: 16px; color: #000000; font-family: arimo, arial, sans-serif; background-color: #ffffff; user-select: text !important;\"\u003e\u003cspan dir=\"auto\" style=\"box-sizing: border-box; user-select: text !important; word-break: break-word; vertical-align: inherit;\"\u003eOs produtos oferecidos neste site são fornecidos exclusivamente para estudos in vitro. Estudos in vitro (do latim: em vidro) são realizados fora do corpo. Esses produtos não são medicamentos e não foram aprovados pelos orgão de saude para prevenir, tratar ou curar qualquer condição médica, enfermidade ou doença. A introdução de qualquer tipo de substância no corpo humano ou animal é estritamente proibida por lei.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Mundo Peptideos","offers":[{"title":"Default Title","offer_id":52914407407979,"sku":null,"price":597.0,"currency_code":"BRL","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0969\/0605\/1947\/files\/1000145540-5ad1adc47a5b29dc8317689261215948-640-0.webp?v=1771698890","url":"https:\/\/www.mundopeptideos.com\/products\/igf-1-lr3-1mg-maximizacao-de-resultados-musculares-diluente-genpharma","provider":"Mundo Peptideos","version":"1.0","type":"link"}